Best Phentermine Alternatives (Updated) Top-Rated Over The Counter Diet Pills

Phentermine is a prescription weight loss medication used by men and women daily. If you or anyone you know is looking for the best phentermine alternatives from the plethora of phentermine alternative supplements from the market by different brands, then keep reading this article.

In this article, we will discuss in detail the five best over-the-counter natural phentermine alternatives on the market that help you lose weight safely by aiding in your weight loss journey.

Below we have given an overview of the 5 OTC phentermine alternatives in a tabular format:

PhenGold This is one of the best Phentermine over-the-counter alternatives on the market that support your weight loss journey by acting as an appetite suppressant.
PhenQ This is an over-the-counter phentermine alternative and a natural appetite suppressant that uses natural ingredients in its formula to help you lose weight safely.
Phen24 This is one of the natural supplements used in place of prescription phentermine to burn fat accumulated in different body parts by activating the process of fat-burning.
PhenAprin This phentermine alternative uses only natural ingredients to reduce excess body fat and promote weight loss in men and women.
Phena-Lean This is one of those phentermine alternatives on the market whose formula helps burn fat and reduce fat production in the human body.

The Top 5 Best Phentermine Alternatives for 2023

In this section, we will discuss the best phentermine over-the-counter weight loss supplements, their ingredients, makers, working, dosage guidelines, health benefits offered, pricing, money-back guarantee, and customer testimonials:


Product Overview
Key Ingredients Green Tea Extract, Green Coffee Bean Extract, Amino Acids, Cayenne Pepper, and Essential Vitamins.
Servings Per Container 30
Side Effects None
Money-Back Guarantee 100-day
Pricing $59.99

PhenGold is one of the top phentermine alternatives available on the market whose multi-action formula contains clinically-proven ingredients to break frustrating plateaus and help jumpstart weight loss. This one of the top weight loss supplements for losing weight comes in easy-to-consume diet pills.

It is a 100% safe, natural, side-effect free, vegetarian-friendly, vegan-friendly, soy-free, gluten-free, dairy-free, non-GMO, filler-free, and artificial ingredients-free natural alternative of Phentermine.

Who Are The Makers Of PhenGold?

The supplier and manufacturer of PhenGold are Health Nutrition Limited. The exhaustively researched formula of PhenGold was formulated and manufactured by experts in an FDA-registered and GMP-certified facility using clinically proven ingredients.

PhenGold Ingredients

The multi-action formula of PhenGold to help you lose weight is made using 100% safe and natural ingredients. The complete list of ingredients used includes green tea (500 mg), green coffee (100 mg), L-theanine (250 mg), L-tyrosine (350 mg), Rhodiola Rosea (250 mg), cayenne pepper (200 mg), caffeine (225 mg), DMAE (150 mg), vitamin B3, vitamin B6, and vitamin B12.

How Does PhenGold Work?

The working of PhenGold is based on its max strength and multi-action formula made using natural and clinically proven ingredients. This weight loss formula helps speed up your weight loss and fat-burning process.

PhenGold prescription drugs aim to hit your target weight so that you feel and look your best. This is done by breaking frustrating plateaus that make losing weight difficult.

When And How To Consume PhenGold?

To boost the production of fat-burning hormones and reduce excess body fat, you are suggested to consume three diet pills at least 20 minutes before your breakfast daily with a full glass of water.

It is strictly prohibited to increase the recommended dosage of three weight loss pills by the makers of this one of the best over-the-counter natural phentermine alternatives.

PhenGold Health Benefits

The essential health benefits of PhenGold are as follows:

  • PhenGold helps activate the body’s fat-burning process to help burn fat accumulated in different parts of your body.
  • It helps boost metabolism and increase energy levels.
  • This powerful multi-action formula helps reduce food cravings and crush sugar cravings, thus acting as an appetite suppressant.
  • The consumption of PhenGold diet pills regularly in the recommended dosage, along with a healthy diet, helps lower calorie intake and promote weight loss.

PhenGold Pricing And Money-Back Guarantee

You can purchase the PhenGold bottles in three different package deals to tackle weight gain.

  • Purchase a one-month supply at $59.99 + free and fast shipping.
  • Purchase a two months supply + one-month free at $119.99 + free and fast shipping.
  • Purchase three months supply + two months free at $179.99 + free and fast shipping.

The makers of this Phentermine over-the-counter alternatives provide its users with a secure 100% satisfaction and a 100-day money-back guarantee.

PhenGold Customer Testimonials

A user of PhenGold from New York, USA, writes,

“Within four weeks of adding PhenGold into my routine, I dropped 9 pounds and lost 2 inches around my waist! Seeing the weight drop off gave me the boost I needed to keep going. And for the first time in months, I can feel my confidence starting to return.”



Product Overview
Key Ingredients Green Coffee Bean Extract, Green Tea Extract, Nopal Cactus, Caffeine, L-Carnitine Fumarate, Capsimax Powder, etc.
Servings Per Container 30
Side Effects None
Money-Back Guarantee 60-day
Pricing $69

PhenQ is an over-the-counter phentermine alternative available on the market whose formula contains five powerful fat scorchers to help you lose weight effectively. This one of the top natural supplements for weight loss comes in easy-to-consume diet pills.

It is a stimulant-free, vegan-friendly, and vegetarian-friendly no-prescription drug that helps support the weight loss journey of men and women.

Who Are The Makers Of PhenQ?

The supplier and manufacturer of PhenQ are Wolfson Brands (UK) Limited. The fat-burning and metabolic-boosting formula of PhenQ was designed and formulated by a team of learned health professionals, nutrition experts, and fitness consultants using high-quality natural ingredients.

The PhenQ weight loss pills were manufactured in FDA-approved facilities in the UK and USA, keeping all the necessary safety guidelines in mind.

PhenQ Ingredients

The PhenQ formula is made using a combination of different weight loss-supporting natural ingredients. These ingredients are alpha-Lacys Reset (a blend of alpha lipoic acid, magnesium, and cysteine base), capsimax powder, chromium picolinate, caffeine, nopal cactus, and L-carnitine fumarate.

How Does PhenQ Work?

The PhenQ diet pills target your weight loss in five ways. These pills target the five critical areas of metabolic health to activate the fat-burning process and burn fat accumulated in different parts of your body like thighs, hips, arms, etc.

The powerful combination of metabolic health-supporting and natural ingredients and a patented alpha-Lacys Reset in this weight loss supplement make this one of the best appetite suppressants that lead to weight loss.

When And How To Consume PhenQ?

To lose weight and maintain a healthy body weight, you are suggested to consume two diet pills daily, wherein one weight loss pill has to be ingested with your breakfast and one with your lunch.

It is strictly prohibited to increase the recommended dosage by the makers of this natural appetite suppressant.

PhenQ Health Benefits

The essential health benefits of using this one of the best phentermine alternatives are as follows:

  • PhenQ helps boost metabolism so that losing weight becomes more effortless.
  • It helps crush food cravings and suppress appetite by inducing the feeling of satiety.
  • This potent formula helps burn fat accumulated in deep layers.
  • The consumption of PhenQ diet pills regularly in the recommended dosage helps increase energy levels and balance mood.

PhenQ Pricing And Money-Back Guarantee

You can purchase the PhenQ bottles in three different package deals to maintain a healthy body weight and physique.

  • Purchase one bottle at $69.99 + free worldwide shipping.
  • Purchase two bottles + one free at $139.99 + free worldwide shipping.
  • Purchase three bottles + two free at $209.99 + free worldwide shipping.

The makers of this natural alternative of Phentermine provide its users with a secure 100% satisfaction 60-day money-back guarantee.

PhenQ Customer Testimonials

A 31-year-old user of PhenQ writes,

“After trying countless diets and lifestyle changes without success, PhenQ helped me lose weight when nothing else worked.”



Product Overview
Key Ingredients Green Tea Extract, Glucomannan, Guarana Extract, Cayenne Powder, Griffonia, Hops, Cayenne, etc.
Servings Per Container 30
Side Effects None
Money-Back Guarantee 60-day
Pricing $69.99

Phen24 is a natural phentermine over-the-counter alternative on the market. It uses its dual-action formula to support weight loss in men and women by boosting metabolism and reducing food cravings during the 24 hours.

It is a safe, effective, vegan-friendly, stimulant-free, chemical-free, non-habit-forming, vegetarian-friendly, and fat-burning supplement.

Who Are The Makers Of Phen24?

Wolfson Brands (UK) Limited designs the dual-action weight loss formula of Phen24 diet pills. A team of health experts and medical professionals designed the 24-hour fat-burning recipe of Phen24.

They formulated two different weight loss formulas of Phen24, one that can be used during the day (Phen24 day formula) for burning fat and another at night (Phen24 night formula) to boost resting metabolic rate.

Phen24 Ingredients

The dual-action formula of Phen24 to help you lose weight is made using natural and high-quality ingredients.

The ingredients used in making the Phen24 day formula are zinc, L-phenylalanine, iodine, guarana extract, copper, cayenne powder, manganese, and caffeine.

The ingredients used in making the Phen24 night formula are green tea extract, glucomannan, molybdenum, Griffonia extract, D-biotin, choline bitrate, chromium, hops (Humulus lupulus L.) extract, thiamine HCl, ascorbic acid, pyridoxine HCl, and calcium D-pantothenate.

How Does Phen24 Work?

The working of Phen24 is based on the cutting-edge dual formula of this supplement made using a blend of natural, high-quality, and clinically proven ingredients. This dual-action formula helps double your weight loss efforts by activating the fat-burning process.

The primary aim of the Phen24 day and night formula is to support the thermogenesis effect in men and women who want to lose weight naturally.

When And How To Consume Phen24?

To maintain healthy blood pressure levels and lose weight, you should consume one Phen24-day formula weight loss pill in the morning. Then, take two Phen24 night formula diet pills at least one hour before bed daily.

The makers of these non-prescription drugs suggest that pregnant or nursing women should consume these counter-diet pills after consulting their health professionals.

Phen24 Health Benefits

The essential health benefits of using this no-prescription medication are as follows:

  • Phen24 helps lower calorie intake and burn more calories.
  • It helps reduce sugar cravings and suppress appetite effectively by inducing the feeling of fullness.
  • This dietary fiber supplement formula helps support thermogenesis so that you lose weight for a slimming effect.
  • Consuming Phen24 diet pills regularly in the recommended dosage helps regulate high blood pressure levels and eliminates stored fat in your body.

Phen24 Pricing And Money-Back Guarantee

You can purchase the Phen24 day and night formula bottles in three different package deals to lose weight and regulate high blood pressure levels effectively.

  • Purchase a one-month supply at $69.99 + free shipping.
  • Purchase a two-month supply and one-month free at $139.99 + free shipping.
  • Purchase a three-month supply and two-month free at $209.99 + free shipping.

The makers of this appetite suppressant provide its users with assured 100% satisfaction 60-day money-back guarantee.

Phen24 Customer Reviews And Testimonials

Several Phen24 reviews by customers mention that this OTC phentermine alternative is one of the best they have tried so far from the market. This supplement’s dual-action formula has helped boost metabolism and effectively support weight loss during the day and night.

A Phen24 user review mentions,

“I dropped 2 dress sizes and I have TONS more energy during the day and night.”



Product Overview
Key Ingredients L-Phenylalanine, L-Taurine, L-Carnitine, Alpha Lipoic Acid or ALA, Caffeine Anhydrous, and others
Servings Per Container 60
Side Effects None
Money-Back Guarantee 35-day
Pricing $39.95

PhenAprin is a natural appetite suppressant on the market that uses its advanced formula to support weight loss in men and women by controlling appetite and burning more calories effectively.

It is a natural, safe, effective, high-quality, and additive-free supplement.

Who Are The Makers Of PhenAprin?

A team of health professionals, weight loss experts, and nutritionists designs phenAprin supplements by Sutra Health. They formulated this supplement using a blend of natural ingredients and manufactured it in a state-of-the-art facility, following all necessary safety guidelines.

PhenAprin Ingredients

The PhenAprin formula is made using different metabolic health-supporting natural ingredients. These key ingredients are L-phenylalanine, theobromine, L-taurine, L-carnitine, and 7-keto (DHEA).

How Does PhenAprin Work?

The primary aim of the PhenAprin supplement is to stimulate the process of thermogenesis in your body, which helps break down fat cells. This supplement promotes a feeling of fullness after eating food in men and women, thus reducing calorie intake effectively.

The consumption of these diet pills works to regulate metabolism, revitalize energy levels, improve mood, and reduce stress levels.

When And How To Consume PhenAprin?

To lose weight, burn fat, and maintain a healthy body mass index, you are suggested to consume one to two diet pills daily of this supplement with a meal of your choice.

It is strictly prohibited to increase the recommended dosage by the makers of this natural appetite suppressant. Also, pregnant or nursing women should consult their health professionals before consuming these weight-loss pills.

PhenAprin Health Benefits

The essential health benefits of using this over-the-counter phentermine alternative are as follows:

  • PhenAprin helps burn excess body fat and accelerate weight loss.
  • It helps crush food cravings and suppress appetite.
  • This potent formula helps boost the rate of metabolism.
  • The consumption of PhenAprin diet pills regularly in the recommended dosage helps stimulate the thermogenesis effect and increase energy levels.

PhenAprin Pricing And Money-Back Guarantee

You can purchase the PhenAprin bottles in the form of two different package deals to maintain healthy blood pressure levels and burn calories.

  • Purchase one PhenAprin bottle pack at $39.95.
  • Purchase two PhenAprin bottles pack at $59.95.

PhenAprin Customer Testimonials

Several PhenAprin reviews and testimonials by customers mention that these phentermine pills are one of the best weight loss pills they have tried so far from the market. This supplement’s metabolic health-supporting formula has helped burn more calories and eliminate stored fat effectively.



Product Overview
Key Ingredients Caffeine Anhydrous, L-Tyrosine, Cayenne Pepper, Ginseng Root Extract, and Bitter Orange Fruit Extract
Servings Per Container 60
Side Effects None
Money-Back Guarantee NA
Pricing $59.99

Phena-Lean is one of the best natural phentermine substitutes available on the market, whose superior blend formula contains scientifically-backed ingredients to fuel the fire within you that helps burn fat and promote weight loss effectively. This one of the best phentermine alternative supplements to lose weight comes in the form of easy-to-consume OTC diet pills.

It is a 100% safe, natural, side-effect-free, additive-free, filler-free, and artificial ingredients-free counter phentermine alternative.

Who Are The Makers Of Phena-Lean?

The brand that manufactures the Phena-Lean supplement is Anabolic Warfare. The body-recomposition formula of this one of the best over-the-counter natural phentermine alternatives was designed by a group of weight loss experts and medical professionals at Anabolic Warfare using a superior blend of natural ingredients.

Phena-Lean Ingredients

The body recomposition formula of Phena-Lean to help you lose weight is made using a superior blend of 100% safe, natural, and effective ingredients. The complete list of ingredients used in Phena-Lean includes Vitamin B3 (25 mg) and its combination (766 mg).

The ingredients included in the Phena-Lean blend are caffeine anhydrous, infinergy (di-caffeine malate), L-theanine, theobromine, ginseng root extract, bitter orange fruit extract, L-tyrosine, cayenne pepper fruit powder, Lean GBB (Gamma Butyrobetaine), paradoxine (grains of paradise fruit), huperzine A 1%, and rauwolscine.

How Does Phena-Lean Work?

The working of Phena-Lean is based on its body recomposition formula made using a superior blend of scientifically proven ingredients. This weight loss formula, along with fast-release technology, helps you lose weight safely by effectively assisting your weight loss journey.

The primary aim of the Phena-Lean prescription drug is to increase your energy levels and expenditure. This is done so that you are ready to sweat more than usual.

When And How To Consume Phena-Lean?

To promote weight loss and reduce fat production, you should start consuming one Phena-Lean weight loss daily in the morning with food. Then, after a few days, you can drink two diet pills daily, one in the morning with food and another before lunch.

The makers prohibit increasing the recommended dose of two Phena-Lean pills.

Phena-Lean Health Benefits

The essential health benefits of using this one of the best phentermine alternatives are as follows:

  • Phena-Lean helps boost energy levels so you remain revitalized and rejuvenated throughout the day.
  • It helps boost metabolism and lose weight and burn fat effectively.
  • This appetite suppressant formula helps reduce food cravings and suppress appetite.
  • Consuming Phena-Lean diet pills regularly in the recommended dosage and a healthy diet helps regulate high blood pressure levels and maintain an average body mass index.

Phena-Lean Pricing And Money-Back Guarantee

You can purchase the Phena-Lean bottles through one-time purchases or auto-delivery subscription deals to help you lose weight.

  • Purchase one time by paying $59.99, along with free shipping.
  • Purchase an auto-delivery subscription every one, two, or three months by paying $47.99 and free shipping on all orders.

Phena-Lean Customer Testimonials

A Phena-Lean user review mentions,

“First off I recommend everything this company sells. They have never let me down. This product along with proper diet and exercise had my stomach flat before I knew it. Highly recommend it along with the detox one.”

Now that we have discussed the best phentermine alternatives on the market, we will be discussing the ranking factors that help us decide on the top phentermine alternatives from the market.

Why Should You Use Natural Phentermine Alternatives Over Prescription?

Many who are looking for a weight-loss solution that is both safe and effective often turn to Phentermine. Millions of people have used Phentermine worldwide to help them lose weight quickly. Still, it also has some severe side effects that can be dangerous, especially if taken over an extended period. That’s why many people have started using natural phentermine alternatives, with minimal side effects and no prescription required.

Safe & Effective

Natural phentermine alternatives are great because they provide a safe and effective solution for those struggling to lose weight. These supplements do not have the same harsh side effects as prescription Phentermine, making them more suitable for long-term use.

Sustainable Weight Loss

Natural phentermine alternatives are also effective for promoting sustainable weight loss. Take Garcinia Cambogia extract as an example; it helps block fat storage in the body while at the same time suppressing appetite so that you can finally reach your ideal body composition without having to starve yourself to achieve results.

Increase Metabolism & Energy Levels

Many natural phentermine alternatives also help increase metabolism and energy levels so you can burn more calories throughout the day and get better results from exercising or dieting. This increased metabolism can also help boost overall health, leading to increased well-being and greater chances of success when trying to lose weight naturally.


Another great reason natural phentermine alternatives should be chosen over prescription drugs is their affordability compared to prescription drugs – which may put a hefty dent in your pocketbook without guaranteeing results!

Natural supplements are much more budget-friendly than taking multiple expensive prescriptions per month, enduring any costly operations or plastic surgery treatments associated with losing weight fast, or simply not being happy with one’s looks as far as physical shape/appearance goes.

The Factors Considered Before Choosing The Best Phentermine Alternatives

Below we have discussed in detail the factors our research and editorial team considered before choosing the best phentermine alternatives from the market.

Company Reputation

The one thing we were the most skeptical about was the company of the over-the-counter phentermine supplement. Therefore, we chose only those weight loss supplements on the market whose company was reputed and known in the market for its products.

We did not want to share information about companies and their OTC phentermine alternatives that were a scam.

Manufacturer Transparency

For this list of the best phentermine alternatives, only those weight loss supplement companies are chosen whose advertisement is honest and transparent. The ad must be realistic and not flashy.

The OTC Phentermine alternative companies that show that you could burn fat and lose weight after taking weight loss pills for just a few days or intend to treat, cure, or prevent any health issue related to weight gain are not at all preferred.


We need to know the ingredients used to make the best phentermine alternatives. We look for weight loss supplements that use high-quality, highly potent, and natural ingredients.

It is a preferred advantage if the chosen weight loss supplement uses scientifically tested and proven natural ingredients for healthy weight loss, like green tea extract, amino acids, natural appetite suppressants, etc.


The characteristics of the phentermine substitutes are one of the top factors we look forward to before curating this list of the best phentermine alternatives. These characteristics only decide the formulation and how Phentermine works on the human body.

The phentermine over-the-counter diet pills that are naturally made and use an additive-free formulation are preferred over many phentermine diet pills that use artificial ingredients and stimulants.


Only those phentermine alternatives were permitted entry into this list with an adequate dosage of natural ingredients in their formula. If the dosage of components is significantly less or more to provide health benefits to the human body, then that phentermine alternative is removed from the list immediately.


In this list, we have chosen those natural phentermine alternatives that provide a healthy dosage of natural ingredients, so the supplement is effective when consumed.

Several customer reviews and testimonials have mentioned that taking the 100% naturally-made formula of any weight loss supplement from this list has provided no significant adverse side effects or allergic reactions to their health. Thus, considered safe for consumption by individuals.


Pricing is one such factor that is most looked upon by the users of weight loss supplements. The users prefer Phentermine over-the-counter supplements available at an affordable rate. Still, we do not prioritize pricing the over-the-counter phentermine alternative.

We choose top Phentermine alternatives whose features and formulation are at par with others, which are affordable but with a not-so-effective formula.

Refund Policy

Users prefer phentermine alternatives by companies that offer a secure 100% satisfaction money-back guarantee on their purchases. Therefore, in this list, we have mentioned only those dietary supplements by companies that accept returns and provide refunds in case the user is unsatisfied with the product.


The reviews and testimonials by users provide us with clear insight into the formulation of the phentermine over-the-counter diet pills, as these reviews by users mentioned online are unedited and unfiltered. Therefore, we look at many reviews regarding choosing the best phentermine alternatives from the market.

The Scientific Evidence-Backing Ingredients In Phentermine Alternatives

In this section, we’ll look at scientific evidence backing up some of the ingredients found in popular Phentermine alternatives so you can make an informed decision.

We will discuss how these ingredients help boost metabolism and suppress appetite so you can lose excess body fat safely and effectively.

Green Tea Extract

Green tea extract (GTE) is an abbreviation of the scientific term ‘Camellia Sinensis Extract.’ It’s derived from Camellia Sinensis leaves and typically includes high concentrations of catechins – powerful antioxidants that are thought to offer numerous health benefits. Catechins are mainly concentrated in green tea because they comprise most of its active ingredients.

The presence of catechins in green tea has been linked with improved metabolism – which can lead to increased fat-burning potential and ultimately result in weight loss or maintenance. The antioxidant properties have also been attributed to reducing inflammation levels – as low-level inflammation has been linked to an increased risk for obesity.

Moreover, studies suggest that green tea can reduce body fat by directly blocking its accumulation through anti-obesity mechanisms such as reduced glucose absorption or decreased triglyceride levels.

Several studies have tested the effects of green tea extract on weight loss. For instance, one study published in 2015 involving 60 participants revealed that those who consumed a capsule containing both caffeine and GTE had a nearly 500% greater reduction in body mass than those who drank only caffeine without GTE after ten weeks.

Garcinia Cambogia

Garcinia cambogia is a small tropical fruit native to South Asia that resembles a pumpkin. Its rind contains hydroxycitric acid (HCA), which has been found to have numerous beneficial effects on health. HCA is responsible for most of the health benefits associated with garcinia cambogia.

Based on research conducted by scientists worldwide, it appears there are several potential mechanisms involved in garcinia cambogia’s ability to promote weight loss:

Suppresses Appetite

Extracts from garcinia cambogia can reduce ghrelin levels, a hormone associated with hunger and food craving. This helps suppress the appetite and makes people feel fuller for longer after eating.

Blocks Fat Production

The hydroxycitric acid present in the rind of garcinia cambogia may block the action of an enzyme called citrate lyase, which plays a vital role in lipid (fat) synthesis within cells. In other words, HCA blocks your body’s ability to create fat from carbohydrates consumed during meals.

Several studies indicate that garcinia cambogia may effectively promote long-term weight loss in specific populations. One study published in the journal “Complementary Therapies in Medicine” showed that overweight adults who took G.cambogia–containing supplements lost significantly more weight than those who took placebo pills.

Cayenne Pepper

The cayenne pepper is a red-hot chili pepper of the capsicum family and is also often called ‘chili pepper.’ It originated in South and Central America but can now be found worldwide as part of various cuisines.

There are many potential benefits associated with taking cayenne pepper in aiding with weight loss; it is believed that the heat from the spice helps boost metabolism by raising your body’s core temperature slightly for a short period after consumption, leading to a more significant calorie burn than would typically occur during restful periods.

A study conducted in 2016 found that subjects who consumed capsules containing 3 mg of cayenne per day experienced reduced appetite levels demonstrating that this spice might have tangible effects on fat deposits in the body when included as part of an overall healthy diet plan over extended periods (six months).

Vitamin B6

Vitamin B6, also known as pyridoxine, is part of the family of compounds known as the vitamin B complex. This group of nutrients helps support a healthy nervous system and cognitive function. It is also a cofactor in many metabolic processes, including energy production, protein metabolism, and immune system support.

Research has found that Vitamin B6 can be essential in maintaining a healthy body weight. Studies have correlated higher dietary intake with lower body fat percentages in overweight children and more nutritional lipid profiles in obese adults.

Additionally, taking Vitamin B6 supplements facilitates satiety during mealtime and potentially decreases caloric consumption.


Glucomannan (gummi-gutta) is considered an indigestible dietary fiber because it doesn’t get absorbed into the bloodstream like other forms of fiber and passes through the body instead. As with all nutritional fibers, glucomannan helps promote digestion and increase fullness after meals.

The leading theory behind using glucomannan to help with weight loss is that it may help reduce appetite by making people feel fuller faster, so they end up eating less than they would without taking glucomannan.

That being said, some studies have indicated that glucomannan may also be effective at helping reduce cholesterol levels and blood sugar levels as well.

This can be beneficial if you are trying to lose weight and have existing health conditions.

A study published in Scientific Reports found that taking a combination of two supplements (one containing 4 grams of glucomannan) significantly decreased hunger levels among test subjects who were overweight or obese after two weeks compared with those who just took a placebo supplement (Krattai et al., 2015).


The stimulant effect of guarana has been shown to increase metabolism, reduce appetite and decrease fat absorption in animal studies. A few human studies have been conducted on how guarana can help with weight loss because it affects metabolic rates and energy production.

In one randomized, double-blind clinical trial comparing the effects of green tea extract (containing both caffeine and epigallocatechin gallate or EGCG) to guarana (containing just caffeine), researchers found significant reductions in body fat mass with both treatments.

The authors suggested this because guarana could boost metabolic activity while reducing food intake due to its appetite-suppressing effects.


Hops contain compounds such as humulone and lupulin that have anti-inflammatory properties and may help reduce body fat. Some studies suggest that hops can improve overall metabolic health by reducing fasting glucose and insulin levels. In addition, hops are a valuable source of dietary fiber that helps reduce appetite and makes it easier for your body to absorb food and other nutrients more efficiently.

In a double-blinded study published in The Journal of International Medical Research, participants were given 250 mg of dry extract of hops per day for 12 weeks alongside their regular diet.

At the end of the study period, researchers observed that the average waist circumference was decreased by 3 cm compared to baseline measurements. In contrast, total body fat had significantly reduced by 8% compared to baseline measurements.


Griffonia simplicifolia is a small shrub reaching up to twelve feet (3.6 meters) in height. The plant has green leaves with white flowers that bloom from April through June and typically produce brown fruits in August and September. Leaves, roots, and seeds are used in traditional African medicine for their alleged healing properties.

Though it’s become popular among some people looking to lose weight, there have been few scientific studies on the ability of Griffonia simplicifolia extract containing 5-HTP or tryptophan to help people lose weight or otherwise improve physical health outcomes positively related to obesity or excess body weight.

In one randomized, double-blind, placebo-controlled clinical trial conducted on 30 adult men between 18 and 50, participants ingested 500 mg of dry Griffonia berries daily for eight weeks.

After the study, researchers noted that none of the participants experienced any significant changes in body weight during the experiment.


Caffeine is believed to increase your metabolic rate, allowing the body to burn more calories throughout the day. Studies show that taking large amounts of caffeine in supplement form can increase your metabolic rate by 3 – 11%.

Caffeine may be able to suppress your appetite, leading to eating less and ultimately resulting in weight loss. One study showed that participants who took high doses of caffeine decreased their calorie intake by 8% compared to those who didn’t take any caffeine.

When we feel tired or sluggish, it can lead to poor food choices or skipping workouts. Caffeine can help boost vigor so you have the motivation to get up and move your body. When taken before exercise, research shows that caffeine may enhance performance and burn fat while aiding weight loss.

Green Coffee Bean Extract

The primary active component in GCBE is chlorogenic acid, an antioxidant-rich molecule in much higher concentrations within green coffee beans than in regular brown ones.

In addition to being high in antioxidants and other beneficial plant compounds, chlorogenic acid has been credited with helping slow down glucose absorption following meals, which keeps your blood sugar levels stable and boosts your metabolism over time.

In 2012, a study was published in the journal Diabetes Metabolic Syndrome and Obesity revealing a powerful metabolic effect when participants took green coffee bean extract for eight weeks.

At the end of this period, those taking green coffee bean extract had lost an average of 17 percent of their body fat compared to those taking the placebo, which only saw a 3 percent decrease in body fat percentage.

FAQs About Phentermine and Supplementation

Q: What Is Phentermine?

A: Phentermine hydrochloride (HCL) is an anorectic medication used for weight loss and as an adjunct to lifestyle modification that helps reduce body weight without compromising safety or efficacy. It works by stimulating the release of norepinephrine and dopamine in the brain, which creates feelings of satiety (fullness).

Because of its appetite suppression effect, Phentermine has been prescribed for obese patients since 1959. The US Food and Drug Administration (FDA) approved Phentermine as an over-the-counter supplement in 2012.

Q: How Long Does Phentermine Last In My System?

A: The length of time that Phentermine stays in your system depends on several factors, including age, gender, health status, diet, and other medications you are currently taking.

Q: Is Phentermine A Controlled Substance?

A: There are no federal restrictions on prescribing or possessing Phentermine except in certain jurisdictions where it may be classified as a controlled substance due to potential abuse. While this is true for most states in the United States, Canada also ranks Phentermine under its Controlled Drugs and Substances Act (CDSA). Europe’s European Council also lists it as a doping agent banned from professional sports competitions.

Q: Can Phentermine Cause Side Effects?

A: Many people experience mild side effects when taking Phentermine. These symptoms usually go away after a couple of weeks. If you experience any side effects, talk to your doctor about what you can do to minimize them.

Q: What Is Phentermine Used For?

A: Phentermine is used as a prescription medication to treat obesity. This drug works by stimulating the brain’s appetite center so that you feel less hungry. When you eat less food, you naturally burn off more calories.

Q: Who Should Not Take Phentermine?

A: People who are sensitive to caffeine should avoid this product. Also, those who suffer from heart disease, high blood pressure, diabetes, thyroid disorders, glaucoma, urinary tract infections, or mental illness should not take Phentermine.

Q: Why Is Phentermine A Schedule IV Controlled Substance?

A: Phentermine is classified as a Schedule IV controlled substance because it has the potential for abuse and addiction when used in high doses for extended periods. As such, there are strict regulations on how it can be prescribed and dispensed.

To obtain Phentermine legally and safely, you must have a valid prescription from your doctor or healthcare provider.

Q: Can You Buy Phentermine Online?

A: It is illegal to purchase medication without a valid prescription including Phentermine. Some sellers offer fake or unregulated versions of the drug for sale on the internet, but these products often contain ingredients that can be dangerous or even deadly. It is never worth risking your health by buying from questionable sources.

Prescription versions of Phentermine can be bought from licensed pharmacies if you have a valid prescription from your doctor. Ensure you only purchase your medication from reputable, verified sources requiring appropriate dispensing documentation. Never buy anything from questionable websites or vendors who claim drugs are available over the counter or without a prescription.

Q: Is It Safe To Buy Phentermine Online?

A: Generally, it’s not safe to buy any medication without a doctor’s prescription because there may be severe health risks associated with taking drugs that are not medically authorized.

Additionally, many counterfeit versions of this drug are available on the market and don’t necessarily contain what they say they do. Therefore, even if a site appears legitimate, there could still be bogus products sold from these sites.

Q: Is Phentermine Dangerous?

A: Phentermine is not considered dangerous when taken as instructed but can become hazardous if misused or abused. People sometimes misuse Phentermine by taking higher doses than prescribed or more frequently than recommended.

Suppose you take too much Phentermine at once or use it more often than directed. In that case, you risk overdosing on the drug, which can lead to serious side effects like elevated blood pressure, seizures, stroke, heart attack, mood swings, impaired judgment, physical dependence, and addiction.

For these reasons, it’s vital that anyone who takes Phentermine follow their doctor’s instructions carefully and not exceed recommended dosage amounts under any circumstances.

If you think that you may have an addiction to Phentermine or are concerned about potential side effects associated with its use, then speak with your doctor immediately for guidance on the next steps.

The Top 5 Best Phentermine Alternatives for 2023 Final Thoughts

To conclude this review of the best over-the-counter phentermine alternatives, we can say that these supplements provide several benefits to the human body, ranging from weight loss to the activation of fat-burning hormones to an increase in energy levels.

Most phentermine substitutes in this list have ingredients like green tea extract, amino acids, appetite suppressants, etc., in common due to their varied benefits. These natural phentermine substitutes have made the weight loss process and journey easier.

To know which OTC phentermine alternative among these mentioned phentermine over-the-counter alternatives is the best for your body, you can compare the best phentermine alternatives mentioned in this list based on their ingredients, characteristics, formulations, benefits, pricing, refund policy, and most importantly, the customer testimonials.

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Please understand that any advice or guidelines revealed here are not even remotely substitutes for sound medical or financial advice from a licensed healthcare provider or certified financial advisor. Make sure to consult with a professional physician or financial consultant before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary and are not guaranteed as the statements regarding these products have not been evaluated by the Food and Drug Administration or Health Canada. The efficacy of these products has not been confirmed by FDA, or Health Canada approved research. These products are not intended to diagnose, treat, cure or prevent any disease and do not provide any kind of get-rich money scheme. Reviewer is not responsible for pricing inaccuracies. Check product sales page for final prices.

Alexandra Lewis

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