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Monday, December 6, 2021

The FDA Approves The Combination Of Covid Vaccinations

(AP) – WASHINGTON, D.C. — On Wednesday, US officials authorized extending COVID-19 boosters to Americans who got the Moderna or Johnson & Johnson vaccinations, as well as saying that anybody who qualifies for an extra dose may get a brand different from the one they initially received.

The FDA’s approvals are a big step in extending the US booster campaign, which began last month with more Pfizer vaccine doses.

The FDA Approves The Combination Of Covid Vaccinations

Before more people get their hands filthy, the CDC will assemble an expert panel on Thursday before making official recommendations on who should get booster shots and when.

The FDA Approves The Combination Of Covid Vaccinations

The new changes would make tens of millions of Americans eligible for booster injections and officially enable mixing and matching of vaccines, making it simpler to obtain a second dosage, especially for individuals who had a negative effect from one brand but still want the proven protection of immunization.

The FDA authorized a third Moderna shot for the elderly and individuals at high risk of COVID-19 because of health problems, work, or living situations six months after their last injection. Moderna’s booster will be half the dose used for the first two injections, based on company evidence showing this was enough to reactivate immunity.

Because the vaccines are made differently and have various dose regimens, FDA rulings vary — and the J&J vaccine is less effective than either of the two-shot Moderna or Pfizer vaccines on many occasions.

The FDA says it is okay to mix and match vaccine brands for boosters, regardless of which immunizations someone received before. The injections’ interchangeability is expected to speed up the booster campaign, particularly in nursing homes and other facilities where patients have received a range of dosages over time.

Given that many people do not remember which vaccine they had, FDA officials said they tried to make the booster recommendations as flexible as possible. Despite this, he thinks many people would choose a booster shot from the same company that gave them their initial attempt.

The CDC decided to mix and match boosters based on preliminary results from a federal study of different booster combinations, which showed that every extra dose increases virus-fighting antibody levels.

Furthermore, the study found that recipients of the single-dose J&J vaccination had a significantly better response if given a full-strength Moderna booster or a Pfizer booster instead of a second J&J injection. In this study, the half-dose Moderna booster was not tried.

According to health authorities, the aim remains to provide first vaccinations to the roughly 65 million Americans who are presently unvaccinated. Even though all three brands continue to protect against hospitalization and death, the booster campaign is designed to shore up viral protection amid signs that vaccine effectiveness is declining against mild diseases.

Because the single-shot J&J vaccine has been shown to provide less protection than its two-shot counterparts, the FDA has recommended that everyone who has gotten it to get a booster injection. Several FDA advisers who backed the booster decision claimed that J&J’s vaccine should have been designed from the outset to need two doses.

A key committee will give more information on who should get booster injections and when. The director must approve their recommendations of the CDC. The Pfizer or Moderna vaccinations were administered to the vast majority of the 190 million Americans fully vaccinated against COVID-19, whereas the J&J vaccine was given to just around 15 million. 

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