‘Light Flash’ Therapy May Slow Alzheimer’s

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As per two new modest trials, treating Alzheimer’s sufferers to an hour of precisely regulated light and/or noise each day appeared to halt that telltale cerebral degradation that characterizes illness development across time. Although pharmaceutical development for Alzheimer’s disease has largely failed, the current study reveals the treatment potential of 2 non-drug tools: lighting and noise.

What? By strengthening and sustaining a specific sort of rhythmic cerebral sound wave called “gamma waves,” that has been shown to decrease in strength in Alzheimer’s sufferers. This research has made the experts hopeful about an option that does not have any evil impact on the brain or body and still helps to cure this disease in a short span.

‘Light Flash’ Therapy May Slow Alzheimer’s

“Our completely noninvasive approach to manipulate the power of gamma brain waves works by simply showing mice or people flickering light and buzzing sound at a particular frequency,” explained Li-Huei Tsai while presenting this research.

Tsai is the head of the Massachusetts University of Technology’s Picower Center for Memory and Learning. She is part of a group of scientists who were the first to apply this sensory-stimulating approach, dubbed “GENUS,” on mice in 2016.

Some other individuals are subjected to regular “fake” treatments of steady lights & background noise as a comparative. 3 months ago, cerebral imaging showed that the therapy collective’s neural activity potency had increased, but indicators of Alzheimer’s-related cerebral deterioration had decreased. With no noticeable adverse effects, the therapy sample also fared higher on following face and surname memory assessments.

'Light Flash' Therapy May Slow Alzheimer's

The accumulation of amyloid plaque in the brains had often been thought to be a major indication of Alzheimer’s disease. The frequency of the light flashes used in the study was chosen to correspond to the native frequencies sweet region of gamma cerebral impulses. The goal of the 2 new studies was to explore if the first accomplishment with mice can be repeated in humans.

Hajos& his coworkers dealt with 74 Alzheimer’s sufferers who ranged from mild to severe. Half of the participants were exposed to identical one-hour every day 40 Hz audible exposure treatments for 6 months. The second half was subjected to regular charade training.

Although cerebral deterioration associated with Alzheimer‘s disease continued to progress in the therapy unit, it did so at a 65 percent lower level as compared to the non-treatment collective.

MihalyHajos, a neurophysiologist and associate lecturer at Yale University School of Medicine, as well as the chief scientific officer of Cognito Therapeutics, Inc. in Cambridge, Mass., led the second trial.

Because both types of research featured limited populations of individuals, Tsai stressed that additional and bigger research is required.

Still, she said she was “cautiously optimistic,” given that both efforts “indicate that GENUS is safe and people tolerate the treatment well; it preserved the brain volume in Alzheimer’s patients; it preserved the connectivity of the brain in Alzheimer’s patients, and it preserved some cognitive and daily function in Alzheimer’s patients.”

Both types of research are discussed during the Alzheimer’s Organisation’s annual conference, which was held simultaneously webcast and also in Denver on Monday. Until it is released in a peer-reviewed publication, such work is regarded preliminary.

“It is encouraging that we are now seeing Alzheimer’s treatment and prevention studies that incorporate a variety of approaches,” she noted, “including traditional drug therapies, lifestyle approaches, and non-drug therapeutic elements such as were used in these studies.”

At the same time, Edelmayer stressed that as a “relatively novel concept,” light and sound therapy is not yet ready for prime time, and “much more research will still be needed to inform whether this could be a safe and effective approach for treatment.”


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